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Reply	Bill says: In agreement with what Phil Manning and some subsequent posters have said, after more than six months without alcohol during chemotherapy, I happily returned to drinking a glass or two of red wine with dinner one night and woke up with a hangover of nearly unimaginable proportions.My oncologist informed me that this is not uncommon after abstaining from alcohol and suggested I increase my tolerance by having a half-glass or less at meals a couple of times a week to upregulate the appropriate liver enzymes. After about two months of gradually increasing doses, I was back to my "usual" tolerance and able to drink two or three glasses of wine or pints of beer at a meal with no significant ill effects the next day.  (no votes) Tags: domestic science, human body.
	posted on 2008-10-30 18:31:00 | Report abuse

Reply	Anonymous says: I like to go on the massive lash pretty much every day, but always like to get 8 hours sleep in between sessions.I often find that I struggle to get the early morning "livener" in but once I've downed a couple I'm off and running.Is this also due to abstinence during the 8-hour sleeping period?  (no votes) Tags: domestic science, human body.
	posted on 2008-11-06 16:21:00 | Report abuse

Reply	Bela de Lune1 says: The true answer is that you brain, after you begin drinking in your youth realizes that you a dimwit and that there is nothing it can do to stop you. Thus, it simply stops rejecting the poison, and even enjoys it itself! This is not a joke - just an easy way to describe a biological phenom.  (no votes) Tags: domestic science, human body.
	posted on 2008-11-07 08:27:00 | Report abuse

Reply	Denitsa says: The moral? If you wanna get maximally drunk with minimal resources-drink irregularly. I have however two questions to those who posted on the mechanisms of getting drunk.First, you mentioned that some medicines are processed with alcohol and if you trash the liver with both of them, you can cause damage. I knew you're not supposed to drink alcohol with antibiotics, but I didn't know about the paracetamol. What other general medicines fall in that group?And also, if you happen to drink for example a glass or two of wine, how damaging that would be to your liver? From my experience, I get dizzy when I'm on antibiotics from just a glass of wine (I know, I know, it happened only once or twice)-yeah, if you wonder on the quantity-I'm a female. My second question-you said that alcohol inhibits glutamate. Is this related to the monosodium glutamate that is added to different products? Does it mean that after getting drunk I will find the soup tasting differently? I'm very curious on that and I'm going to test it tonight if chance allow, but still, am I right? And could someone explains the glutamates and what they do? I'm very curious.http://tothefuturewithlove.blogspot.com  (no votes) Tags: domestic science, human body.
	posted on 2008-11-07 14:42:00 | Report abuse

Reply	Anonymous says: It seems strange to me that some people never manage to develop tolerance to alcohol yet others do. I have friends who are lifelong boozers who always get drunk after a certain amount, I envy them, because the amount I need to feel drunk is probably life-threatening. I think the brain is at work t a certain extent, because if drinking alone the beer buzz is much delayed, yet iof drinking with friends and having a laugh, the beer buzz arrives earlier.  (no votes) Tags: domestic science, human body.
	posted on 2009-01-16 16:51:00 | Report abuse

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